PinE3

Among over 600 human E3 ligases, representative E3 ligases utilized for TPD account for only about 1%, including CRBN and VHL.
Pin selected about 30 E3 ligases suitable for drug development through literature and experimental analysis out of a total of about 600 E3 ligases.
We have established a platform technology to efficiently identify new binders with improved drug properties in a short period of time.